Intact and middle‐down CIEF of commercial therapeutic monoclonal antibody products under non‐denaturing conditions
نویسندگان
چکیده
منابع مشابه
Phase behavior of an intact monoclonal antibody.
Understanding protein phase behavior is important for purification, storage, and stable formulation of protein drugs in the biopharmaceutical industry. Glycoproteins, such as monoclonal antibodies (MAbs) are the most abundant biopharmaceuticals and probably the most difficult to crystallize among water-soluble proteins. This study explores the possibility of correlating osmotic second virial co...
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ژورنال
عنوان ژورنال: ELECTROPHORESIS
سال: 2020
ISSN: 0173-0835,1522-2683
DOI: 10.1002/elps.202000013